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Regeneron Stock Slides Despite Strong Q1 Results And A New Share Repurchase Program

Aditya Raghunath4 minute read
Reviewed by: Thomas Richmond
Last updated Apr 30, 2026

Key Stats for Regeneron Stock

  • Price change for Regeneron stock: -6%
  • $REGN Share Price as of Apr. 29: $686
  • 52-Week High: $821
  • $REGN Stock Price Target: $878

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What Happened?

Regeneron (REGN) stock is down over 9% in the last five trading sessions despite the company reporting a solid Q1. On paper, the results look good.

  • Total revenues grew 19% year-over-year to $3.61 billion.
  • Non-GAAP earnings per share rose 15% to $9.47.
  • Dupixent, the company’s flagship drug, posted $4.9 billion in global net sales, up 31% on a constant currency basis.

So why is Regeneron stock down?

  • A few things spooked investors. The biggest issue is EYLEA. Combined U.S. sales for EYLEA and EYLEA HD came in at $942 million, but regular EYLEA US sales fell 36% year-over-year as patients switched to the newer EYLEA HD version.
  • On top of that, the FDA missed its April deadline to rule on the EYLEA HD pre-filled syringe application. That decision is still pending, and the uncertainty around it clearly rattled the market.
  • There was also a setback in oncology. An experimental drug combination targeting lung cancer will not move forward to late-stage trials.

That’s a pipeline disappointment, even if management downplayed it on the earnings call.

REGN Stock Q1 Earnings vs. Estimates in Billion USD (TIKR)

Despite all the good news, including FDA approval of a new gene therapy called Otarmeni for genetic hearing loss (which Regeneron is offering for free), and a new $3 billion share repurchase program, none of it was enough to offset these concerns.

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What the Market Is Telling Us About Regeneron Stock

Regeneron stock often gets punished when EYLEA disappoints. The drug has been a major revenue driver for years, and investors are closely watching the transition to EYLEA HD. Any regulatory delay or slower-than-expected adoption raises questions.

The share buyback is a positive signal. Management clearly believes the stock is undervalued. But right now, the market is focused on the risks, not the reassurances.

REGN Stock Valuation Model (TIKR)

Regeneron stock has a strong long-term story, especially with Dupixent continuing to grow and a deep pipeline across oncology, rare diseases, and obesity. But today, the negatives are winning.

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How Much Upside Does Regeneron Stock Have From Here?

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Disclaimer:

Please note that the articles on TIKR are not intended to serve as investment or financial advice from TIKR or our content team, nor are they recommendations to buy or sell any stocks. We create our content based on TIKR Terminal’s investment data and analysts’ estimates. Our analysis might not include recent company news or important updates. TIKR has no position in any stocks mentioned. Thank you for reading, and happy investing!

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