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Down 56% in Five Years, Here’s Why Grifols Stock Could Deliver 16% Annual Returns Going Forward

Gian Estrada7 minute read
Reviewed by: Thomas Richmond
Last updated Jan 7, 2026

Key Takeaways:

  • Price Projection: Based on current assumptions, Grifols stock could reach €15 by December 2027 from a current price near €11, reflecting earnings recovery rather than aggressive rerating.
  • Return Profile: This scenario represents a 36% total return over roughly two years, equivalent to approximately 17% annualized returns, assuming execution remains on track.
  • Model Inputs: The valuation is built on 6% revenue growth, operating margins reaching 20%, and an 11x exit P/E which are all consistent with a normalized plasma-derived therapies business.
  • Earnings Recovery: Upside is primarily driven by margin normalization and deleveraging progress, as free cash flow improves and balance sheet pressure continues to ease.

Run your own valuation on Grifols for free and stress-test earnings normalization, margin recovery, and deleveraging assumptions through 2027 →

Grifols S.A (GRF) is in the middle of a reset phase as management works to stabilize earnings, strengthen cash flow, and unwind leverage after an extended period of balance sheet pressure. 

The company is emerging from a multi-year balance sheet reset as EBITDA rises toward €2 billion and free cash flow turns sustainably positive, easing refinancing risk and restoring gradual financial flexibility.

Recent results show third-quarter revenue of €2 billion, supported by mid-single-digit organic growth, while EBITDA margins in the mid-20s, reaching about 25% in 2024 and trending toward 26–27% over the next few years, signal improving cost control after several years of margin pressure.

Profitability is stabilizing as plasma collection volumes recover in the U.S., operating efficiency improves, and management prioritizes cash generation to support debt reduction across a market capitalization of roughly €7 billion.

With shares up about 14% in 2025, investors are beginning to price in a recovery scenario. The key question now is whether Grifols can sustain execution long enough for deleveraging and margin normalization to translate into durable shareholder returns.

Run a free valuation on Grifols to see how earnings normalization and improving cash flow could affect returns through 2027 →

What the Model Says for Grifols Stock

Based on our valuation model through December 2027, Grifols stock could rise from €11 to €15 which is a total of 37.8% return over roughly 2.1 years.

That translates to an expected 16.2% annualized return, which sits firmly in the mid-teens range and is consistent with a recovery-driven investment rather than a high-growth rerating story.

The upside is driven mainly by earnings normalization, as the model assumes 5.7% annual revenue growth, 19.9% operating margins, and a conservative 11.5x exit P/E, all of which are in line with Grifols’ historical performance during more stable operating periods.

Under these assumptions, Grifols appears modestly undervalued, with returns coming from operational improvement and balance sheet stabilization rather than aggressive multiple expansion.

Grifols Stock Valuation Model (TIKR)

See how Grifols’ valuation changes as plasma supply and margins normalize, free with TIKR →

Our Valuation Assumptions

TIKR’s Valuation Model lets you plug in your own assumptions for a company’s revenue growth, operating margins, and P/E multiple, and calculates the stock’s expected returns.

Here’s what we used for GRF stock:

1. Revenue Growth: 5.7%

Grifols has historically delivered mid-single-digit revenue growth supported by structural demand for plasma-derived therapies and limited global collection capacity across regulated markets.

Revenue expanded about 7% annually over the past five years and 8% over ten years, reflecting periods of capacity build-outs and post-pandemic volume recovery rather than steady-state conditions.

Current execution prioritizes normalized plasma collection, operational stability, and balance sheet repair, limiting near-term upside from aggressive capacity or geographic expansion.

According to consensus analyst estimates, a 5.7% revenue growth assumption balances resilient immunoglobulin demand and gradual utilization recovery against disciplined capital allocation and near-term throughput constraints.

2. Operating Margins: 19.5%

Grifols’ profitability profile reflects a recovery phase, with margins improving as plasma availability stabilizes and fixed collection and manufacturing costs are absorbed across higher volumes.

Recent margin pressure stemmed from elevated operating costs and normalization after peak utilization years, placing current profitability below historical cycle highs.

Incremental margin improvement is supported by easing cost pressures, tighter expense control, and operational leverage rather than material changes to pricing or revenue mix.

In line with analyst consensus projections, operating margins around 20% represent partial normalization driven by utilization recovery and cost discipline while remaining appropriately below prior peak profitability levels.on recovery and cost discipline while remaining appropriately below prior cycle peaks.

3. Exit P/E Multiple: 11.5x

The valuation framework reflects improving financial quality rather than a full earnings re-rating, as the stock continues to trade at compressed multiples following prolonged volatility.

Balance sheet progress has been meaningful, with net leverage declining from about 5x to near 4x EBITDA, reducing refinancing risk and dilution concerns.

EBITDA margins have recovered into the mid-20% range and free cash flow has turned positive year over year, supporting earnings durability without implying aggressive multiple expansion.

Based on street consensus estimates, an 11.5x exit multiple reflects improving cash generation and declining leverage while acknowledging investor caution after several years of uneven earnings performance.

What Happens If Things Go Better or Worse?

Different scenarios for Grifols stock through 2027 illustrate how outcomes vary depending on margin recovery and earnings execution (these are estimates, not guaranteed returns):

  • Low Case: The business keeps growing ~5%, but the market stays skeptical. The multiple remains compressed, and returns come mainly from slow compounding, at ~12% per year.
  • Mid Case: Growth stays in the 5–6% range and sentiment stabilizes. The stock tracks fundamentals with little multiple change, producing ~16–17% annual returns.
  • High Case: Growth is still only ~6%, but sentiment improves and the valuation re-rates higher. Even modest multiple expansion pushes returns toward ~20% per year.

Grifols outcomes now depend more on execution and margin repair than aggressive growth.

GRF Stock Valuation Model (TIKR)

From €11 today to a €20 target, the model implies roughly 16% annualized returns if normalization plays out.

Use TIKR’s valuation model for free to estimate what Grifols could be worth (It’s free) →

How Much Upside Does Grifols Stock Have From Here?

With TIKR’s new Valuation Model tool, you can estimate a stock’s potential share price in under a minute.

All it takes is three simple inputs:

  1. Revenue Growth
  2.  Operating Margins
  3.  Exit P/E Multiple

If you’re not sure what to enter, TIKR automatically fills in each input using analysts’ consensus estimates, giving you a quick, reliable starting point.

From there, TIKR calculates the potential share price and total returns under Bull, Base, and Bear scenarios so you can quickly see whether a stock looks undervalued or overvalued.

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Disclaimer:

Please note that the articles on TIKR are not intended to serve as investment or financial advice from TIKR or our content team, nor are they recommendations to buy or sell any stocks. We create our content based on TIKR Terminal’s investment data and analysts’ estimates. Our analysis might not include recent company news or important updates. TIKR has no position in any stocks mentioned. Thank you for reading, and happy investing!

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